They kindly asked that we schedule an immediate check and diagnostic testing at our local vet. Fortunately for conscientious dog moms and dads, Simparica offers a once-a-month chewable treatment that is FDA-approved and safe for Fido, taking the guesswork out of fighting fleas and ticks. Did you ever get to the bottom of redness in eyes? Each month he got sicker and sicker. He has trouble raising his leg to urinate. It's getting better and I decided to just wait and hope when this stuff clears out in 30 days he goes back to normal. This simple-to-give oral monthly treatment protects dogs against heartworm disease as well as against ticks and fleas and intestinal worms like roundworms and hookworms. Im praying over him too . Gave my Olde English Bulldog puppies Simparica Trio on 4/7/21 they are almost 4 month now. My dogs have been throwing up since then and I could not for the life of me figure out why. and now i'm on an hour by hour let's see if she will perk up. I give my dogs Simparica at the beginning of each month. Today is Friday. Instead it has become a world of greed. As of today, Sadie's ability to eventually meet the strict certification requirements in that pursuit, remains guarded, although her progress prior to this event had been stellar. This drug has caused our dog to loose his footing and not eat. She probabpy had some in her system (which is quite common, even for well-cated-for puppies), which would explain her diarrhea. Then he came too . My 3 month old shih tux Juno took her second dose last week and for the last two days shes vomited and has been eating grass nonstop! It is recommended to wash your hands after administering this medication. I dont know what to do to get this out of their system?? I even told them about the Simparica which they dont respond to. Simparica may show slide side effects in a few dogs like tremors, unsteadiness, and/or seizures but else it is Tested and FDA approved suits to 90% of dogs. This drug needs to be pulled off the market! If your dog has reactions to this medicine, push fluids! We took him to a emergency Vet Hospital that pin pointed Simparica Trio as the main facture that triggered his controlled seizure episodes in having constant all day tremors & seizures hurting him to the point of making the decision to put him down or have him continue with the pain until it killed him. Simparica Trio also prevents heartworms and keeps hookworms and roundworms from harming your pup. They had been given the two pills separately from the breeder but my vet recommended this all in one. Some dogs improve, some don't, not a clear answer why. Final Thoughts on Trifexis vs Simparica. No this puppy hasnt had seizures and I came to this forum to see other problems with this medicine. No more of this med! Those with Diarrhea symptom, did it look like mucus in their pets stool? Humans can get infected with certain intestinal parasites, and fleas sometimes bite people. Stay safe! My 11 year old mini Aussie has been taking Simparica 1.5 years. This junk needs to be pulled from the market. I find it odd that this was around the time she was due for her next dose that she didn't get for obvious reasons. Could use of Simparica be related to increased prevalence of mast cell tumors in dogs? Now Im scared ive been giving him Simparica Trio and it could be the cause of his progressively worsening sickness. She has what is called knuckling. Just after the 4th dose he started to collapse at his feeding dishes on the floor, next we raised dishes and he did ok for being shaky but continued to decline to the point where he could not use dishes , and now cant eat or drink. I disagree. He has been on just Simparica with no problems. Animal Drug Safety Communication: FDA Alerts Pet Owners and Veterinarians About Potential for Neurologic Adverse Events Associated with Certain Flea and Tick Products, How to Report Problems with Flea and Tick Products, An official website of the United States government, : I just hope and pray she gets better. I did find another one in New Hampshire but I know like everyone else that all we be negative just like all tests done so far. He returned to vet, rec'd an allergy injection, first in his life, plus Penicillin x 10 days. Our dog was killed by this poison within 15 hours after taking one dose. This is so awful. Today she has fallen 2 or 3 times in the last 8 hours). We gave our one year old Simparica tonight and he started having trimmers that lasted on and off for about 30 minutes. This is terrible. Simparica may cause abnormal neurologic signs such as tremors, unsteadiness, and/or seizures. Why the vets use this treatment after so many side effects being reported is disgusting. Somedays he will have 2 and then he will go for a couple days without having any issues. Hope your pup is doing better!! Use with caution in dogs with a history of seizures. My 14 year old, 3.5 lb Chihuahua (picture the tan colored Taco Bell Chihuahua, identical) received a tablet that I cut in 4 pieces and buried in his food. Thank u Fox I have good news I did get 2 additional in house potassium test done and they both came back normal. This is because drugs in the isoxazoline class have been associated with neurologic reactions including seizures, tremors, and ataxia in dogs with or without a history of neurologic disorders. I don't know if the lump came from it or something else. If you're not already protecting your dog from common disease-causing parasites, then it's time to schedule a visit to your veterinarian. I am so upset - I gave it to him last week and he had an accident in the house. This was days ago when I could still get food into him and the result. His first was a week after taking his simparica. I hope the best for you and dog, I know its a tough time. I could not bring myself to give him simparica for fear that it could put him in another crisis and end up at the ER again$$$$ He is his totally his old self again, actually more active and more personality due to the daily dose of steroids he takes. If it has been a long period of time since the last dose was given, you may see fleas temporarily during the missed time. Will not eat or drink. Chewable tablets can be given directly to your dog or broken up and mixed with food. We are currently going through this with our nine year old dachshund. Been also very lethargic not wanting to get out of bed. I am so mad at myself for letting the vet talk me into this. He has been dribbling pee and no longer has a stream and for obvious reasons is asking to go out way more often than his usual. Get practical pet health tips, articles, and insights from our veterinary community delivered weekly to your inbox. Vet thought was inner ear infection now thinking otherwise. Discuss Simparica chewable treats with your veterinarian when looking for a safe, effective way to arm your dog against biting parasites and the diseases they carry. Compared to other products, the efficiency of this . Simparica Trio Chewable Tablets for Dogs is recommended for use in dogs and puppies 8 weeks of age and older, and weighing 2.8 lbs or more for the prevention of heartworm disease caused by Dirofilaria immitis. I'm besides myself. We are beyond sad and livid! Today March 20 (8 week old) I get a message saying the puppy ate one of these pills that was for the bigger dog she already owned. She has been very unpredictable and snapping at people but this is improving. I thought maybe my dog had a bladder infection or got into something that upset her gut. Nobody knows what causes it or makes one dog recover and another not. this is how Simparica works on insects who bite your dog. They want another blood draw in 3 weeks to see where she is. I will never give my dog this medication again. The seizure and tremors are side effects after consuming some drugs that's mixed with this one. Can you tell me if your dog is back to normal now?!?! The vet does not feel it is due to Simparica but i think it could be. The main side effect of Simparica Trio is the risk of heartworm disease in dogs. She's been given this dosage for over a year. Before he took his first doe of Simparica he was fast running, and flying through the house and yard. I also lost my dog due to simparia Trio. My vet recommended this for my puppy, he is now lethargic, has blood in stool, and can hardly stay awake. I started giving my aussie shepherd simparica at 4 months. The innovative formula disrupts gamma-aminobutyric acid (GABA) and glutamate receptors, which both play a role in nerve transmissions. So we went home with her on steroids and more antibiotics and denamrin for liver. I hope this comment will save you and your pets from unnecessary trouble. Any believers out there please say a prayer for our pup as I will for the people on this thread. He seems dehydrated. We live in Texas and I have only used an isoxazoline preventative when insect populations get out of control in my area, like they are now. Simparica is available by prescription only, so discuss any history your dog has of seizure disorders with your veterinarian when determining the best flea and tick treatment for your pet. A few hours later, he began vomiting nonstop. Ive spent over $3,000 on vet bills for at least four visits to the ER and follow up lab work including X-rays. Any suggestion? iI hope she will not have any other problems. Vet said they dont think it has anything to do with the Simparica. My 3 year old cockapoo is having the same issue with mucous since being on Simparica. Ive read these stories and am also disgusted. Has anyone recently started simpatico trio on their fur baby and noticed any kidney problems? i know this med did this to her , she was on for a year and half , i should never ever have listened to the vet and went with my gut, but again they assured me since she was healthy be very rare she would have side effects smdh and plus been in contract with the makers of this horrible medication they all should be ashamed of themselves!!!!!!!!!!! Then they come back! It is like night and day compared to her regular personality or demeanor. Next day, he was suddenly 1000% worse, would not touch food, could not move. Has odd agitated swallowing when not eating anything. So sad as he was once a happy healthy dog with no prior health issues. Simparica Trio is considered safe for dogs as young as eight weeks old who weigh at least 2.8 pounds. Very small sample - many deformities, stillborn. His motor skills have been affected and hes been losing weight even though he eats heartily. However, the product has not been evaluated in breeding, pregnant, or lactating dogs. If it was due to the Simparica, then it would expected to be resolved within a day or two. Those jaw spasms have decreased but were pretty alarming in Dec and January. My chihuahua was given this three weeks back, I actually requested I kept my old treatment but they assured me it was safe and good. Update on my Labradoodle who started seizures just a few hours after receiving first dose of Simparica on T-Day 2020 it is March 2021 and my Vet put my dog on Phenobarbital for anti-seizure med. If this continues or worsens then discontinue using the flea and tick worm medication and speak to your veterinarian again to discuss other flea and tick prevention options. On 08/06 she threw up. Wonder why PetSmart offers this if there are so many concerns reported. Vet did all kinds of tests but said it couldnt be simparica. Some years back my husband gave vet approved & sold oral flea/tic medication to each of our 2 Standard Poodles. You can do this by reporting to the drugs manufacturers, who are required to report this information to the FDA, or by submitting a report directly to the FDA. She seems so much happier in herself but until she comes off the keppra completely I wont know if it's a reversible problem. We had family in for the weekend and he was not himself. I wish I would have came across this before I gave my healthy 9 month old puppy this medication two days ago. I will not be giving him simparica again. Seizures have been reported in dogs receiving isoxazoline class drugs, even in dogs without a . Glad i held off on the free sample i was given! Each medication combats different pests. My poor baby! If there are enough reports they may have to pull it off the market until further safety tests can be done. Started in February and within a couple of weeks ears started twitching. My 10 year old Standard Poodle had one dose of Simparica and had seizures two weeks later, which was yesterday. During this period coincidentally I have noticed a change in his behaviour. It's 5:53pm and he's acting very lethargic. She had some itching and a bit lethargic but is eating very well. Would appreciate any opinion you all may have. Strictly natural with zero side effects from now on. When fleas or ticks bite the dog, they are exposed to the drug and killed during their blood meal. Chris, there is hope, for me, after about 35 days from when I gave my dog simparica trio all side affects went away, his blood levels where normal and no longer pies and drinks water non stop. I originally wanted to get Nexgard, but for some odd reason, when I had went to my vet to pick it up, instead they gave me this. A dog fence is an important detail to consider when adopting a pet for the first time or moving your dog to a new home. However, these adverse effects are rarely observed in pets and overall the product is proven to be suitable for all dogs without the occurrence of any side effects. It kills heartworm larvae by causing paralysis that leads to the death of the parasite. I have an appointment this Wednesday but not sure if Im going to keep it if the cough will go away eventually. Gave my 28lb German Spitz her monthly prescibed dose of Simparica. It is Easter Sunday and he still has diarrhea and drinking a crazy amount of water. Follow the directions on the drug label for Simparica or Simparica Trio or as provided by your veterinarian. Im beside myself. I gave my morkie poo simparica trio from age 4 months until age 1 on advice of his vet. 98. How is your puppy doing? But he still is suffering from lethargy, polyuria and polydispia basically still drinks and pees non stop. All we want to do is take the best care of our animals and trust the people (Vet's) who specialize in this to do what's right for them. He had ONE dose that evening and completely lost his appetite within a couple days. The diarrhea and vomiting went away after a few days but the cough has lingered for over a month now even with treatment. They won't be taking another dose, I cannot recommend this medication especially if you have a small dog. Will be talking to the vet inregards to his side effects. 2-6 days in vomiting here and there. I used to use revolution but they dont cover ticks as well. He first started with seizures and losing weight in June after giving him Simparica. It started working on him right away, Diarrhea. Then on day 5 my poor dog just couldnt move. Simparica is available in different doses for dogs 2.8 pounds and over, but has not been evaluated for use in pregnant, breeding or nursing pets. 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