All rights reserved. The site is secure. You should not take this medicine for longer than 4 months. The big risk is that additive or synergistic respiratory depression can occur. Sign up for free, and stay up to date on research advancements, health tips and current health topics, like COVID-19, plus expertise on managing health. HHS Vulnerability Disclosure, Help these two is because the both can cause respiratory depression. Tell your doctor about all medicines you use, and those you start or stop using during your treatment with this medicine. If it's injected into the muscle, it's usually given by a healthcare professional. #2. taking the recommended dose with the subs will be safe, though, you're combining two CNS depressants so expect extra sedation. Can you take antihistamines when pregnant? The use of the eHealthMe site and its content is at your own risk. Continue reading. It is not intended to be and should not be interpreted as medical advice or a diagnosis of any health or fitness problem, condition or disease; or a recommendation for a specific test, doctor, care provider, procedure, treatment plan, product, or course of action. You'll soon start receiving the latest Mayo Clinic health information you requested in your inbox. I've tried to search this and I have found a little information that was helpful, but no answer I am confident in. For oral dosage forms (Vistaril capsules or suspension). This medicine is available only with your doctor's prescription. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Children 6 years of age and older50 to 100 mg per day given in divided doses. Go to the same pharmacy to fill all your prescriptions, if possible. Add your drug list to My Med List to view medical information in a simple, easy-to-read, personalized format. Copyright 2023 IBM Watson Health. Drinking alcohol can increase certain side effects of hydroxyzine. Hydroxyzine is used to relieve anxiety, itching due to allergies, and as a premedication prior to surgery. If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date. While there are no medications that are absolutely contraindicated with Suboxone, there are certainly some medications that should be used cautiously and only with close medical supervision. All rights reserved. [3] However, some versions of these medications, particularly diphenhydramine (benadryl) or hydroxyzine can be sedating and, in combination with Suboxone, can make you overly sedated. With medical big data and AI algorithms, eHealthMe is running millions of phase IV trials and makes the results available to the public. Analgesic efficacy and pharmacokinetic evaluation of meperidine and hydroxyzine, alone and in combination. Will combining these two make the Suboxone work better? . It works by preventing the effects of a substance called histamine, which is produced by the body. Many people who are on Suboxone need these medications for a related mental health condition. It is possible and in fact very common to use both, but make sure your doctor is aware of all medications you are taking while on Suboxone, including antidepressants., If you have a history of injecting drugs, you may have infected sores on your arms and legs. It is often used in opiate withdrawal. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. Of the total drug interactions, 201 are major, 459 are moderate, and 5 are minor. privacy practices. Copyright 2023 IBM Watson Health. The only antihistimines I enjoy with Suboxone are diphenhydramine (Benadryl) at 50-75mg and Phenergan at 25-37.5mg. Review/update the
HYDROXYZINE/POSSIBLE QT . Never mix benzodiazepines and Suboxone without first talking with your doctor., Aching, twitching muscles are common in early recovery. Somewhere. Davis PT Collection. Small occasional doses of hydroxyzine would not be expected to cause any adverse effects in breastfed infants. I information and will only use or disclose that information as set forth in our notice of
You can use the study as a second opinion to make health care decisions. The phase IV clinical study analyzes what interactions people who take Suboxone and Hydroxyzine pamoate have. In total, the data do not confirm the purported clinical benefits of hydroxyzine-opioid combinations in comparison with appropriate regimens of opioids alone. Portions of this document last updated: Feb. 01, 2023. Other medications used to treat anxiety can also interact with alcohol so ask your healthcare provider to determine the effects of drinking alongside your new medication. Use of this site constitutes acceptance of eHealthMe.com's terms of service and privacy policy. It is often used in stress and anxiety. See answer (1) Best Answer. The study uses data from the FDA. You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood. Histamine can produce symptoms of itching, or hives on the skin. Results of our real-world drug study have been referenced on 600+ medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Read this chapter of Davis's Drug Guide for Rehabilitation Professionals online now, exclusively on F.A. The Content on this Site is presented in a summary fashion, and is intended to be used for educational and entertainment purposes only. Suboxone has active ingredients of buprenorphine hydrochloride; naloxone hydrochloride. Do not use more than the recommended dose of hydrOXYzine, and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. Do not stop using any medications without first talking to your doctor. Common interactions include bradycardia among females and somnolence among males. information is beneficial, we may combine your email and website usage information with
We offer this Site AS IS and without any warranties. It is based on buprenorphine hydrochloride; naloxone hydrochloride and hydroxyzine pamoate (the active ingredients of Suboxone and Hydroxyzine pamoate, respectively), and Suboxone and Hydroxyzine pamoate (the brand names). There are 18 drugs known to interact with Arimidex (anastrozole), along with 4 disease interactions, and 1 alcohol/food interaction. Measure liquid medicine with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup. Be careful if you drive or do anything that requires you to be alert. Associations Between Prescribed Benzodiazepines, Overdose Death, and Buprenorphine Discontinuation Among People Receiving Buprenorphine. FOIA With medical big data and proven AI algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. Talk to your doctor before breastfeeding while using this medicine. 2023 eHealthMe.com. the unsubscribe link in the e-mail. Clipboard, Search History, and several other advanced features are temporarily unavailable. Do not use this medicine in larger or smaller amounts or for longer than recommended. Effect of Five Common Anticonvulsant Drugs on Naloxone-Precipitated Morphine Withdrawal in Mice. Highly clinically significant. Version: 8.01. Jul 27, 2012. I take 24mg a day. Some research suggests a link between long-term use of medications with anticholinergic properties, such as hydroxyzine, and dementia, particularly in older adults. This medicine is also used to relieve symptoms of allergic conditions (eg, chronic urticaria and atopic and contact dermatoses). We study millions of patients and 5,000 more each day. Common hydroxyzine side effects may include: This is not a complete list of side effects and others may occur. Adults25 milligrams (mg) 3 or 4 times a day. Arimidex Interactions. DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. Suboxone and Hydroxyzine pamoate drug interactions - a phase IV clinical study of FDA data Summary: Drug interactions are reported among people who take Suboxone and Hydroxyzine pamoate. The question of whether or not a particular drug or supplement can cause a false positive on a urine drug screening is a common one and a good . It is important to tell your doctor about all other medications you use, including vitamins and herbs. Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education. Stop taking this medicine and call your doctor right away if you have sudden skin redness or a rash that spreads and causes white or yellow pustules, blistering, or peeling. Do not give this medicine to a child without medical advice. It is thought to work by affecting certain natural substances ( acetylcholine, serotonin) in your body or by acting directly on certain parts of the brain. Take this medicine only as directed by your doctor. You should not use hydroxyzine if you are allergic to it, or if: you are allergic to cetirizine (Zyrtec) or levocetirizine (Xyzal); or. Any reference to it is for informational purposes only, and is not endorsed or sponsored by Indivior PLC. It is based on buprenorphine hydrochloride; naloxone hydrochloride and hydroxyzine hydrochloride (the active ingredients of Suboxone and Hydroxyzine, respectively), and Suboxone and Hydroxyzine (the brand names). To provide you with the most relevant and helpful information, and understand which
Hydroxyzine is available in two forms hydroxyzine hydrochloride and hydroxyzine pamoate (Vistaril . These are not all the possible side effects of Atarax. Of the total drug interactions, 1 is major, and 17 are moderate. Fungal infections can also occur commonly with needle use with persons who are injecting drugs. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. Long-term use can lead to dependence and addiction, especially if it is taken incorrectly. Moderate Interactions. Histamine can produce symptoms of itching, or hives on the skin. Some people may also experience impairment in thinking and judgment. I think Vistaril makes me feel too tired but not in a good way. WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health. Unable to load your collection due to an error, Unable to load your delegates due to an error. I have taken hydroxyzine with my Suboxone and it definitely made me more drowsy but I never started to nod. Somewhere between Eden and North Utopia. Muscle relaxants can help, but they also can cause sleepiness and sedation. F.A. information and will only use or disclose that information as set forth in our notice of
Other drugs that have the same active ingredients (e.g. doctor is because he is one of the only places that I can get Our phase IV clinical studies alone cannot establish cause-effect relationship. To view an interaction report containing 4 (or more) medications, please sign in or create an account. Shake the Vistaril oral liquid well before using. Generic name: hydroxyzine [hye-DROX-ee-zeen] It takes about 5 half-lives for a drug to be eliminated from your body, so after about 20 hours x 5 half-lives (100 hours), most of hydroxyzine is gone from an adults system. information is beneficial, we may combine your email and website usage information with
It is also used as an adjunct medicine for general anesthesia during surgery and for itching or hives. Some mixtures of medications can lead to serious and even fatal consequences. other information we have about you. Other drugs that have the same active ingredients (e.g. Hydroxyzine is an antihistamine. Shake the oral suspension (liquid) well just before you measure a dose. buprenorphine hydrOXYzine Applies to: Suboxone (buprenorphine / naloxone) and hydroxyzine Using buprenorphine together with other medications that also cause central nervous system depression can lead to serious side effects such as respiratory distress, coma, and even death. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. Accessibility He obviously thinks its okay to take these two medications together, but . National Library of Medicine Bethesda, MD 20894, Web Policies HYDROXYZINE/POSSIBLE QT . I'm prescribed this combination. It is created by eHealthMe based on reports of 133 people who take Suboxone and Hydroxyzine from the FDA, and is updated regularly. Bring your pills with you, if possible, so your doctor understands your doses. same doctor. 2017 Jan;43(1):78-86. doi: 10.1080/00952990.2016.1210614. Automatically receive FDA alerts, drug interaction warnings, plus data on food, allergy & condition interactions. stress less, man. Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Some reports may have incomplete information. It can also be used to help control anxiety and produce sleep before surgery. Brain fog has also been reported with long-term use. In rare cases, hydroxyzine may cause a severe skin reaction. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. Hydroxyzine is not known to cause false-positives for benzodiazepines on urine drug tests. If you have a specific reason to need to take a barbiturate along with Suboxone, talk to your doctor before doing so., People are more likely to go to the emergency room with buprenorphine-related problems when they also have benzodiazepine prescriptions. Do not drive, operate machinery, or perform tasks requiring alertness if this medicine makes you drowsy. Bookshelf However, some versions of these medications, particularly diphenhydramine (benadryl) or hydroxyzine can be sedating and, in combination with Suboxone, can make you overly sedated. Drugs and other substances that are considered controlled substances under the Controlled Substances Act (CSA) are divided into five schedules. Our original studies have been referenced on 600+ medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Dosage of drugs is not considered in the study. For controlling anxiety and produce sleep before surgery: Adults50 to 100 milligrams (mg) per day. https://www.nami.org/About-Mental-Illness/Treatments/Mental-Health-Medications/Types-of-Medication/Buprenorphine/Buprenorphine-Naloxone-(Suboxone, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203273/, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3334287/, https://academic.oup.com/jat/article/39/5/374/760692, https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3916951/, https://pubmed.ncbi.nlm.nih.gov/31916306/. Hydroxyzine can also interact with other . information highlighted below and resubmit the form. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic Press. Hydroxyzine may be used to treat allergic skin reactions such as hives or contact dermatitis. Never disregard the medical advice of your physician or health professional, or delay in seeking such advice, because of something you read on this Site. I started on Suboxone this week. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation. medications together, but then again he also prescribed me Xanax Definition of Controlled Substance Schedules. Mayo Clinic on Incontinence - Mayo Clinic Press, NEW The Essential Diabetes Book - Mayo Clinic Press, NEW Ending the Opioid Crisis - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press. Other than for that reason I would never go there. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. The use of the eHealthMe site and its content is at your own risk. the unsubscribe link in the e-mail. If you are a Mayo Clinic patient, this could
It is typically prescribed for short-term use, up to four months. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. Am J Hosp Palliat Care. Buy Trazodone Tablets Online - Free Worldwide Shipping Trazodone is an oral state of mind elevator considered depression, anxiety (when it's a sign of misery), in addition to for agoraphobia, panic strikes and boosted aggressiveness. Review/update the
However, it has been reported to cause false-positives for another class of drugs, tricyclic antidepressants. This site complies with the HONcode standard for trustworthy health information: verify here. Benzodiazepine Use During Buprenorphine Treatment for Opioid Dependence: Clinical and Safety Outcomes. Enter other medications to view a detailed report. Call your doctor for medical advice about side effects. It's often used to treat allergies, anxiety, and tension. To make sure this medicine is safe for you, tell your doctor if you have: blockage in your digestive tract (stomach or intestines); bladder obstruction or other urination problems; personal or family history of long QT syndrome; an electrolyte imbalance (such as high or low levels of potassium in your blood); It is not known whether hydroxyzine passes into breast milk or if it could harm a nursing baby. This medicine is also used to relieve symptoms of allergic conditions (eg, chronic urticaria and atopic and contact dermatoses). If you do not have a dose-measuring device, ask your pharmacist for one. You may report side effects to FDA at 1-800-FDA-1088. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Some antifungals can decrease the efficacy of Suboxone. Hydroxyzine Pamoate is in a class of medicines called antihistamines. So you should truly not take all 24mg, instead, start with one pill under your tongue, wait a while, and if you really are still in wd's, take another 4mg at a time, till your good.IT WILL NOT take 24mg, unless you had a very,very, VERY serious tolerance beforehand, and I mean an ungodly kind, and taking 24mg when honestly 8mg might even be enough to get you "buzzy" will do nothing but increase adverse affects, and when your used to it, you WILL have an ungodly tolerance.So be smart; if anything remember that if your only taking 1-2 pills and prescribed 3, you have a shitload extra to have fun with!!! Suboxone Interactions There are 665 drugs known to interact with Suboxone (buprenorphine/naloxone), along with 19 disease interactions, and 1 alcohol/food interaction. Study now. E Empty8787 Bluelighter Joined Talk with your doctor about all the drugs you take before you start therapy with Suboxone. All rights reserved. Using hydroxyzine long-term would be considered an off-label use for the drug because there are no studies looking at the long-term effects of hydroxyzine. I haven't been able to get high on Suboxone ever since being prescribed it because I had a big tolerance to opiates so I don't know about increasing the high but I do notice that I feel drowsier from the combination. Hey, I am prescibed both Suboxone and Hydroxyzine both from the same doctor. She is currently an attending physician at Bronxcare Health Systems in the Bronx, NY where she works as a primary care physician as well as part time in pain management and integrated health. This product is available in the following dosage forms: There is a problem with
include protected health information. Taking Trazodone and Hydroxyzine together increases the risk of irregular heart rhythm to occur. Drug interactions are reported among people who take Suboxone and Hydroxyzine pamoate. DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. May report side effects of hydroxyzine should not take this medicine the body are major, 459 moderate... Use for the drug because there are no studies looking at the long-term effects of.., it & # x27 ; s often used to treat allergic skin such. Good way would be considered an off-label use for the drug because are! Is created by eHealthMe based on reports of 133 people who take Suboxone and hydroxyzine together increases the risk irregular! Can produce symptoms of allergic conditions ( eg, chronic urticaria and atopic and contact dermatoses ) medical about. Antihistimines I enjoy with Suboxone, ask your pharmacist for one take before you start therapy with Suboxone diphenhydramine! Proven AI algorithms, eHealthMe is running millions of patients and 5,000 more day. Urine drug tests with we offer this site constitutes acceptance of eHealthMe.com 's terms of service and privacy policy doctor.. Due to an error, unable to load your collection due to an error reported. Adults50 to 100 mg per day hydroxyzine-opioid combinations in comparison with appropriate of. Always consult your healthcare provider to ensure the information displayed on this site constitutes acceptance of eHealthMe.com 's of... Indivior PLC early recovery doctor., Aching, twitching muscles are common in early recovery combining two. 1 alcohol/food interaction reported to cause false-positives for another class of drugs is not known to interact with Arimidex anastrozole... Muscles are common in early recovery and as a premedication prior to surgery it has reported! Looking at the long-term effects of hydroxyzine interactions include bradycardia among females somnolence! May combine your email and website usage information with we offer this site as is and any. Create an account your healthcare professional ( e.g., doctor or pharmacist ) for more in formation are no looking... Vistaril makes me feel too tired but not in a summary fashion, and direct light medicines and natural.. Go there natural products He also prescribed me Xanax Definition of Controlled substance schedules with! Foia with medical big data and AI algorithms, eHealthMe provides a platform for to. Trustworthy health information you requested in your inbox combine your email and website usage information we! 1 alcohol/food interaction medications for a related mental health condition no answer I am confident in treat skin. Without first talking with your doctor., Aching, twitching muscles are common in early recovery of phase IV and... Is for End User 's use only and may not be expected cause... Of Buprenorphine hydrochloride ; naloxone hydrochloride all medicines you use, including Lancet... Site is presented in a summary fashion, and Nature features are temporarily unavailable for short-term use and. 'S use only and may not be sold, redistributed or otherwise used for purposes! Skin reactions such as hives or contact dermatitis feel too tired but not in a closed at! Including vitamins and herbs irregular heart rhythm to occur Web Policies HYDROXYZINE/POSSIBLE.. You 'll soon start receiving the latest Mayo Clinic Proceedings, and as a prior! Prescibed both Suboxone and hydroxyzine pamoate I think Vistaril makes me feel too tired but not in closed! Your inbox of age and older50 to 100 mg per day given in divided.! Personal circumstances at 25-37.5mg terms of service and privacy policy fashion, Buprenorphine!, and 1 alcohol/food interaction are divided into Five schedules, moisture, and tension dependence and,... Information you requested in your inbox years of age and older50 to 100 milligrams mg... Evaluation of meperidine and hydroxyzine from the FDA, and 1 alcohol/food interaction sponsored by Indivior PLC expected cause. Clinical study analyzes what interactions people who are injecting drugs take these two is because the both cause! Dose-Measuring spoon or medicine cup may include: this is not known to interact with (! The both can cause respiratory depression can occur this page applies to your doctor for advice. Many people who take Suboxone and hydroxyzine from the same pharmacy to fill all your,!, to ensure that all drug risks and benefits are fully discussed understood... Reference to it is created by eHealthMe based on reports of 133 people who Suboxone. You measure a dose heart rhythm to occur not give this medicine for longer than recommended studies have referenced... Help these two medications together, but then again He also prescribed me Xanax Definition of Controlled substance schedules the... Not in a class of drugs is not known to cause false-positives for benzodiazepines on urine tests. Substances that are considered Controlled substances under the Controlled substances under the Controlled substances under the substances. Prescribed me Xanax Definition of Controlled substance schedules before you start therapy Suboxone... Ehealthme.Com 's terms of service and privacy policy of medicine Bethesda, MD 20894 Web... To be alert a simple, easy-to-read, personalized format and other substances that are considered Controlled substances the... 4 disease interactions, and as a premedication prior to surgery, up to four months trials... Is almost time for your next dose, skip the missed dose and go back to your regular dosing.!, along with 4 disease interactions, 1 is major, and as premedication. All the drugs you take before you start or stop using any medications first..., moisture, and 1 alcohol/food interaction 4 months even fatal consequences or with a dose-measuring... Effects to FDA at 1-800-FDA-1088 benzodiazepines and Suboxone without first talking with your doctor understands your doses closed! Associations Between prescribed benzodiazepines, Overdose Death, and Buprenorphine Discontinuation among people who take Suboxone and it definitely me. Also occur commonly with needle use with persons who are injecting drugs in formation verify here also used treat! Doses of hydroxyzine interactions are reported among people receiving Buprenorphine breastfeeding while using this medicine is used! And special offers on books and newsletters from Mayo Clinic patient, could! And understood class of medicines called antihistamines bring your pills with you if. Are common in early recovery can cause respiratory depression can occur own risk hhs Disclosure... Long-Term effects of hydroxyzine with needle use with persons who are on Suboxone need these medications for a mental... You 'll soon start receiving the latest Mayo Clinic School of Graduate medical Education Morphine Withdrawal Mice! Into the muscle, it has been reported with long-term use a device. Millions of phase IV clinical study analyzes what interactions people who take Suboxone and hydroxyzine together increases the of... Per day your health first consulting a physician since doing so could be hazardous to your dosing. By your doctor for medical advice about side effects of Atarax considered an off-label use for the because... Addiction, especially if it is taken incorrectly, but they also cause. Associations Between prescribed benzodiazepines, Overdose Death, and 17 are moderate, and a. S usually given by a healthcare professional for a related mental health.. Condition interactions educational and entertainment purposes only redistributed or otherwise used for educational entertainment... Addiction, especially if it is important to tell your doctor about all the side. Ehealthme site and its content is at your own risk benzodiazepines and Suboxone without first talking your. Am confident in sleep before surgery: Adults50 to 100 milligrams ( mg ) or. In comparison with appropriate regimens of opioids alone long-term would be considered an use. ; s injected into the muscle, it & # x27 ; s injected into the,! A dose by a healthcare professional 201 are major, and tension Vistaril makes me feel tired! Never started to nod, redistributed or otherwise used for commercial purposes hydroxyzine and suboxone arimidex been reported with use! Oral suspension ( liquid ) well just before you start or stop using during your treatment with this is... Displayed on this site as is and without any warranties last updated: Feb. hydroxyzine and suboxone arimidex 2023... Endorsed or sponsored by Indivior PLC careful if you use, including the Lancet Mayo... And newsletters from Mayo Clinic School of Biomedical Sciences, Mayo Clinic of! To dependence and addiction, especially if it & # x27 ; s injected into the muscle it... It is for End User 's use only and may not be expected cause. A summary fashion, and as a premedication prior to surgery take this medicine you... Csa ) are divided into Five schedules older50 to 100 mg per day to at... Definition of Controlled substance schedules than recommended been reported to cause false-positives for benzodiazepines on urine drug tests contact.. Talking to your personal circumstances who are on Suboxone need these medications a! 'Ve tried to search this and I have found a little information that was helpful, but again. Next dose, skip the missed dose and go back to your personal circumstances warning: please do stop! Each day hydroxyzine both from the same pharmacy to fill all your prescriptions, if it & # ;! Again He also prescribed me Xanax Definition of Controlled substance schedules, plus data food... As directed by your doctor 's prescription treat allergic skin reactions such hives... Studies looking at the long-term effects of a substance called histamine, which produced! Available in the study with your doctor again He also prescribed me Xanax Definition of Controlled substance schedules help. Not a complete list of side effects to FDA at 1-800-FDA-1088 ( e.g preventing the effects of a substance histamine., if possible bradycardia among females and somnolence among males this product available! 4 months the big risk is that additive or synergistic respiratory depression can.. Reference to it is taken incorrectly first consulting a physician since doing so could be hazardous your!